StackTerminal.Health

BETA

Glycine

Inhibitory neurotransmitter & structural amino acid; 3 g before bed shows evidence for improving sleep quality & reducing daytime fatigue.

sleeprecoveryconnective-tissue
Evidence last reviewed: 04 Apr 2026
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Biomarkers studied
Outcomes directly measured across the evidence records below
Sleep
Sleep Quality (subjective)
Cognitive
Cognitive Function
Evidence
2 records
Daytime sleepiness & performance after sleep restriction
Healthy adults with partial sleep restrictionRCT (double-blind, placebo-controlled, crossover)
PUBMEDModerate

3 g glycine before bed significantly reduced daytime sleepiness, fatigue, & cognitive impairment following 25% sleep restriction; mechanism involves core body temperature reduction via SCN NMDA receptors.

Dose: 3000 mgDuration: 3 nightsForm: nullTiming: before bed
Well-tolerated at 3 g; higher doses not well-characterized for sleep specifically.
Collagen synthesis / connective tissue support
Recreationally active malesRCT (mechanistic)
PUBMEDModerate

15 g gelatin (rich in glycine & proline, with vitamin C) before intermittent exercise doubled collagen synthesis markers (P1NP) vs. placebo; glycine is the most abundant amino acid in collagen (~33%).

Dose: 15000 mgDuration: Acute (pre-exercise)Timing: pre-exercise
Study used gelatin + vitamin C, not isolated glycine; glycine is rate-limiting for collagen synthesis.
Forms
Glycine powder or capsules
3 g taken before sleep; sweet taste makes powder palatable.

Stacks containing Glycine

Public community stacks that include this ingredient.

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sleepwomens-health

Cycle-phase support focused on calm & sleep quality without stimulants.

Vitex agnus-castus
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Glycine
3000mg
L-Theanine
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sleep

Improves sleep quality without heavy sedation or melatonin.

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Designed to support sleep quality, parasympathetic activation, & overnight recovery without heavy sedation.

Magnesium Glycinate
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longevityanti-agingcellular-health

Bryan Johnson's Blueprint Longevity Mix is the core daily powder from his self-quantified anti-aging protocol. It combines NAD+ pathway support (CaAKG), collagen precursors (Glycine, Lysine, Vitamin C), joint protection (Glucosamine, Sodium Hyaluronate), mitochondrial support (Creatine, CoQ10-adjacent), and antioxidant defence (Glutathione, Taurine). Every ingredient is dosed at clinically relevant levels validated through continuous biomarker tracking.

Creatine Monohydrate
2500mg
Calcium Alpha-Ketoglutarate (CaAKG)
2000mg
Taurine
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Built from your selected goals, constraints, diet, & the supplement evidence library. You can edit doses & timing.

Magnesium (Glycinate)
400mg
Melatonin
3mg
Glycine
3000mg
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sleep

Supports parasympathetic activation before sleep.

Apigenin
50mg
Glycine
3000mg
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recoverysleepfocus

Supports training consistency under physical & mental stress.

Ashwagandha
600mg
Glycine
3000mg
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recoverysleep

Supports sleep onset with minimal next-day grogginess.

Melatonin
3mg
Glycine
3000mg
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